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Before Polio vaccination was available, 13,000 to 20,000 cases were reported each year in the U.S. None were reported in 2000.

Measles is one of the most infectious diseases in the world, and is frequently imported into the U.S. If vaccinations were stopped, 2.7 million measles deaths worldwide could be expected.

Before the vaccination, Hib meningitis killed 600 children a year, and infected 20,000. If we were to stop immunizing, we would likely return to the pre-vaccine numbers of infections and deaths.

Whooping Cough-Before immunization, up to 260,000 cases were reported in the U.S. each year, with up to 9,000 deaths. Pertussis still occurs worldwide.

Rubella-Before the 1965 vaccination was used routinely in the U.S., rubella resulted in an estimated 20,000 infants born with CRS, 2,100 neonatal deaths and 11,250 miscarriages in a two-year time span.

Chickenpox was responsible for an estimated 4 million cases, 11,000 hospitalizations and 100 deaths each year before the licensing of the chickenpox vaccine in 1995.

Hepatitis B-Approximately 25% of children who become infected with life-long hepatitis are expected to die of a related disease as adults. In addition to the 12,000 infants infected by their mother during birth, approximately 33,000 children under the age of 10 were infected before the vaccination.

Diphtheria-The death rate before vaccinations was up to 20% in the young and elderly. Although Diphtheria is primarily in other countries, international travels make it easy to contract. In 1921, a diphtheria outbreak caused 12,230 deaths in the U.S. Only one case was reported in 1998, due to vaccinations.

Tetanus-Approximately 30% of reported cases of tetanus end in death. Tetanus kills 300,000 newborns and 30,000 birth mothers worldwide, from lack of immunization. Tetanus is not contagious, and can only be prevented by immunization. People of all ages can be infected.

Mumps-Before the vaccination was developed in 1967, an estimated 212,000 cases occurred in the U.S. annually. In 1986 and 1987, there was a resurgence of mumps with 12,848 cases reported. Since 1989, the incidence has declined, with a total of 323 cases last year.

WHO summaries
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